Altered Dopamine Activity after Recovery from Restricting-Type Anorexia Nervosa
نویسندگان
چکیده
منابع مشابه
Plasma nesfatin-1 concentrations in restricting-type anorexia nervosa.
Restricting-type anorexia nervosa (AN-R) is characterized by chronic food restriction and severe emaciation due to various cognitive biases such as a distorted self-image. In spite of several treatments, AN-R continues to be a refractory disease because of its unknown pathogenesis. Although previous studies have shown that changes in feeding regulatory peptides such as ghrelin are involved in a...
متن کاملDopamine and anorexia nervosa.
We have suggested that reduced food intake increases the risk for anorexia nervosa by engaging mesolimbic dopamine neurons, thereby initially rewarding dieting. Recent fMRI studies have confirmed that dopamine neurons are activated in anorexia nervosa, but it is not clear whether this response is due to the disorder or to its resulting nutritional deficit. When the body senses the shortage of n...
متن کاملAltered insula response to sweet taste processing after recovery from anorexia and bulimia nervosa.
OBJECTIVE Recent studies suggest that altered function of higher-order appetitive neural circuitry may contribute to restricted eating in anorexia nervosa and overeating in bulimia nervosa. This study used sweet tastes to interrogate gustatory neurocircuitry involving the anterior insula and related regions that modulate sensory-interoceptive-reward signals in response to palatable foods. MET...
متن کاملReduced 5-HT2A receptor binding after recovery from anorexia nervosa.
BACKGROUND Several lines of evidence suggest that a disturbance of serotonin neuronal pathways may contribute to the pathogenesis of anorexia nervosa (AN). This study applied positron emission tomography (PET) to investigate the brain serotonin 2A (5HT2A) receptor, which could contribute to disturbances of appetite and behavior in AN. METHODS To avoid the confounding effects of malnutrition, ...
متن کاملDouble-blind placebo-controlled administration of fluoxetine in restricting- and restricting-purging-type anorexia nervosa.
BACKGROUND Anorexia nervosa is an often chronic disorder with high morbidity and mortality. Many people relapse after weight restoration. This study was designed to determine whether a selective serotonin reuptake inhibitor would improve outcome and reduce relapse after weight restoration by contributing to maintenance of a healthy normal weight and a reduction of symptoms. METHODS We adminis...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Neuropsychopharmacology
سال: 1999
ISSN: 0893-133X
DOI: 10.1016/s0893-133x(99)00053-6